BDBM50004641 4-(2-Chloro-phenyl)-6-methyl-2-[4-(6-methyl-imidazo[2,1-b]thiazol-5-yl)-phenyl]-5-(pyridin-2-ylcarbamoyl)-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester::CHEMBL320900

SMILES: CCOC(=O)C1=C(NC(C)=C(C1c1ccccc1Cl)C(=O)Nc1ccccn1)c1ccc(cc1)-c1c(C)nc2sccn12

InChI Key: InChIKey=CFSAOLMFARGDEU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Cavia porcellus)	BDBM50004641 (4-(2-Chloro-phenyl)-6-methyl-2-[4-(6-methyl-imidaz...) Show SMILES CCOC(=O)C1=C(NC(C)=C(C1c1ccccc1Cl)C(=O)Nc1ccccn1)c1ccc(cc1)-c1c(C)nc2sccn12 |c:9,t:5| Show InChI InChI=1S/C33H28ClN5O3S/c1-4-42-32(41)28-27(23-9-5-6-10-24(23)34)26(31(40)38-25-11-7-8-16-35-25)19(2)36-29(28)21-12-14-22(15-13-21)30-20(3)37-33-39(30)17-18-43-33/h5-18,27,36H,4H2,1-3H3,(H,35,38,40)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of PAF-induced aggregation of rabbit washed platelets.				J Med Chem 35: 3115-29 (1992) BindingDB Entry DOI: 10.7270/Q28W3DX8
					More data for this Ligand-Target Pair