BDBM50005069 5,7-Dichloro-4-(2-thiophen-3-yl-acetylamino)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL58784

SMILES: OC(=O)[C@H]1C[C@H](NC(=O)Cc2ccsc2)c2c(Cl)cc(Cl)cc2N1

InChI Key: InChIKey=RGNRIMFSKMOPJP-QWHCGFSZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005069 (5,7-Dichloro-4-(2-thiophen-3-yl-acetylamino)-1,2,3...) Show SMILES OC(=O)[C@H]1C[C@H](NC(=O)Cc2ccsc2)c2c(Cl)cc(Cl)cc2N1 Show InChI InChI=1S/C16H14Cl2N2O3S/c17-9-4-10(18)15-11(5-9)19-13(16(22)23)6-12(15)20-14(21)3-8-1-2-24-7-8/h1-2,4-5,7,12-13,19H,3,6H2,(H,20,21)(H,22,23)/t12-,13+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair