BDBM50005354 CHEMBL245610

SMILES: COC(=O)CC1N(C(=Nc2ccccc12)N(C)CCCCCN1CCCC1)c1ccccc1

InChI Key: InChIKey=XJHWSJMWAMLTTJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated T-type calcium channel (Homo sapiens (Human))	BDBM50005354 (CHEMBL245610) Show SMILES COC(=O)CC1N(C(=Nc2ccccc12)N(C)CCCCCN1CCCC1)c1ccccc1 |c:7| Show InChI InChI=1S/C27H36N4O2/c1-29(17-9-4-10-18-30-19-11-12-20-30)27-28-24-16-8-7-15-23(24)25(21-26(32)33-2)31(27)22-13-5-3-6-14-22/h3,5-8,13-16,25H,4,9-12,17-21H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of human T-type calcium channel alpha1G in HEK293 cells				Bioorg Med Chem Lett 20: 38-41 (2010) Article DOI: 10.1016/j.bmcl.2009.11.049 BindingDB Entry DOI: 10.7270/Q2MS3V0M
					More data for this Ligand-Target Pair