BDBM50005394 8-Isopropyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL142410

SMILES: CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C)C

InChI Key: InChIKey=QZADLMGDGWDQNX-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50005394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine A1 receptor (GUINEA PIG)	BDBM50005394 (8-Isopropyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C)C Show InChI InChI=1S/C14H22N4O2/c1-5-7-17-12-10(15-11(16-12)9(3)4)13(19)18(8-6-2)14(17)20/h9H,5-8H2,1-4H3,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity carried out with [3H]-cyclohexyladenosine in guinea pig forebrain membranes against adenosine A1 receptor				J Med Chem 34: 466-9 (1991) BindingDB Entry DOI: 10.7270/Q2154G0Z
					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM50005394 (8-Isopropyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C)C Show InChI InChI=1S/C14H22N4O2/c1-5-7-17-12-10(15-11(16-12)9(3)4)13(19)18(8-6-2)14(17)20/h9H,5-8H2,1-4H3,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor using N6-[3H]cyclohexyladenosine as radioligand in guinea pig forebrain membranes				J Med Chem 35: 924-30 (1992) BindingDB Entry DOI: 10.7270/Q2NS0VJZ
					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50005394 (8-Isopropyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C)C Show InChI InChI=1S/C14H22N4O2/c1-5-7-17-12-10(15-11(16-12)9(3)4)13(19)18(8-6-2)14(17)20/h9H,5-8H2,1-4H3,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity against adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide as radioligand in rat striatal membranes.				J Med Chem 35: 924-30 (1992) BindingDB Entry DOI: 10.7270/Q2NS0VJZ
					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50005394 (8-Isopropyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C)C Show InChI InChI=1S/C14H22N4O2/c1-5-7-17-12-10(15-11(16-12)9(3)4)13(19)18(8-6-2)14(17)20/h9H,5-8H2,1-4H3,(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity carried out with [3H]5'-(N-ethylcarbamoyl)-adenosine in the presence of 50 nM cyclopentyladenosine in rat striatal membranes against...				J Med Chem 34: 466-9 (1991) BindingDB Entry DOI: 10.7270/Q2154G0Z
					More data for this Ligand-Target Pair