null

SMILES: CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCc1nc(C)cc(n1)C(F)(F)F

InChI Key: InChIKey=GNUSAABXOXWQNT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50005489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50005489 (CHEMBL138701 | CHEMBL3234262) Show SMILES CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCc1nc(C)cc(n1)C(F)(F)F Show InChI InChI=1S/C20H17F3N4O3S/c1-3-27-14-7-8-15(12-5-4-6-13(18(12)14)19(27)28)31(29,30)24-10-17-25-11(2)9-16(26-17)20(21,22)23/h4-9,24H,3,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at full-length RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assay				Eur J Med Chem 78: 431-41 (2014) Article DOI: 10.1016/j.ejmech.2014.03.065 BindingDB Entry DOI: 10.7270/Q2W66N9X
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50005489 (CHEMBL138701 | CHEMBL3234262) Show SMILES CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCc1nc(C)cc(n1)C(F)(F)F Show InChI InChI=1S/C20H17F3N4O3S/c1-3-27-14-7-8-15(12-5-4-6-13(18(12)14)19(27)28)31(29,30)24-10-17-25-11(2)9-16(26-17)20(21,22)23/h4-9,24H,3,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at Gal4-fused RORgamma (unknown origin) expressed in 293T cells after 24 hrs by luciferase reporter gene assay				Eur J Med Chem 78: 431-41 (2014) Article DOI: 10.1016/j.ejmech.2014.03.065 BindingDB Entry DOI: 10.7270/Q2W66N9X
					More data for this Ligand-Target Pair