BDBM50005630 CHEMBL3235050

SMILES: CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)c1cc(nn1C)-c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=RBQFJWHBUCVSCF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50005630 (CHEMBL3235050) Show SMILES CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)c1cc(nn1C)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C34H42N4O4/c1-5-8-22-41-33-24-29(40-23-12-21-38(6-2)7-3)19-20-30(33)35-34(39)32-25-31(36-37(32)4)26-15-17-28(18-16-26)42-27-13-10-9-11-14-27/h9-11,13-20,24-25H,5-8,12,21-23H2,1-4H3,(H,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Woosuk University Curated by ChEMBL					Assay Description Inhibition of biotinylated human RAGE assessed as bound amyloid beta level after 60 mins by ELISA				Eur J Med Chem 79: 128-42 (2014) Article DOI: 10.1016/j.ejmech.2014.03.072 BindingDB Entry DOI: 10.7270/Q2C82BTF
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