BDBM50005633 CHEMBL3235374

SMILES: CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)c1cc(nn1C)-c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1

InChI Key: InChIKey=BPFIWOZDVMGAQI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Advanced glycosylation end product-specific receptor (Homo sapiens (Human))	BDBM50005633 (CHEMBL3235374) Show SMILES CCCCOc1cc(OCCCN(CC)CC)ccc1NC(=O)c1cc(nn1C)-c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C35H41F3N4O4/c1-5-8-21-45-33-23-29(44-22-9-20-42(6-2)7-3)18-19-30(33)39-34(43)32-24-31(40-41(32)4)25-10-14-27(15-11-25)46-28-16-12-26(13-17-28)35(36,37)38/h10-19,23-24H,5-9,20-22H2,1-4H3,(H,39,43)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Woosuk University Curated by ChEMBL					Assay Description Inhibition of biotinylated human RAGE assessed as bound amyloid beta level after 60 mins by ELISA				Eur J Med Chem 79: 128-42 (2014) Article DOI: 10.1016/j.ejmech.2014.03.072 BindingDB Entry DOI: 10.7270/Q2C82BTF
					More data for this Ligand-Target Pair