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BDBM50005759 (+/-)-Benzyl-carbamic acid 1-ethyl-3a-methyl-1,2,3,3a,8,8a-hexahydro-1-aza-cyclopenta[a]inden-5-yl ester::CHEMBL286690

SMILES: CCN1CC[C@]2(C)C1Cc1ccc(OC(=O)NCc3ccccc3)cc21

InChI Key: InChIKey=PVMNTYXKDFRXKP-IAXKEJLGSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005759   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetylcholinesterase


(Homo sapiens (Human))		BDBM50005759
PNG
((+/-)-Benzyl-carbamic acid 1-ethyl-3a-methyl-1,2,3...)
Show SMILES CCN1CC[C@]2(C)C1Cc1ccc(OC(=O)NCc3ccccc3)cc21
Show InChI InChI=1S/C22H26N2O2/c1-3-24-12-11-22(2)19-14-18(10-9-17(19)13-20(22)24)26-21(25)23-15-16-7-5-4-6-8-16/h4-10,14,20H,3,11-13,15H2,1-2H3,(H,23,25)/t20?,22-/m0/s1
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Similars
PubMed
n/an/a 69n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human AchE (Acetylcholinesterase)

J Med Chem 35: 1429-34 (1992)


BindingDB Entry DOI: 10.7270/Q2RN38GQ
More data for this
Ligand-Target Pair