BDBM50005872 CHEMBL3236272
SMILES: Ic1ccc(CCCC(=O)N2CCC[C@H]2C(=O)N2CCCC2)cc1
InChI Key: InChIKey=LGGATUIPMFLLJI-KRWDZBQOSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prolyl endopeptidase (Sus scrofa) | BDBM50005872 (CHEMBL3236272) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of porcine prolyl oligopeptidase using Z-Gly-Pro-AMC as substrate after 60 mins by double-reciprocal plot analysis | Eur J Med Chem 79: 436-45 (2014) Article DOI: 10.1016/j.ejmech.2014.04.014 BindingDB Entry DOI: 10.7270/Q2G162BW | |||||||||||
More data for this Ligand-Target Pair |