BDBM50006391 6'-chloro-3'-methyl-1'H,2H,5H-spiro[imidazolidine-4,4'-quinazoline]-2,2',5(3'H)-trione::CHEMBL65372

SMILES: CN1C(=O)Nc2ccc(Cl)cc2C11NC(=O)NC1=O

InChI Key: InChIKey=QBRYBUXHTFUNRQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50006391 (6'-chloro-3'-methyl-1'H,2H,5H-spiro[imidazolidine-...) Show SMILES CN1C(=O)Nc2ccc(Cl)cc2C11NC(=O)NC1=O Show InChI InChI=1S/C11H9ClN4O3/c1-16-10(19)13-7-3-2-5(12)4-6(7)11(16)8(17)14-9(18)15-11/h2-4H,1H3,(H,13,19)(H2,14,15,17,18)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL					Assay Description Tested in vitro for inhibitory activity against partially purified aldose reductase from male rabbit lens				J Med Chem 35: 2085-94 (1992) BindingDB Entry DOI: 10.7270/Q2V123RK
					More data for this Ligand-Target Pair