BDBM50006836 2-[2-(5-Bromo-1H-indol-3-yl)-vinyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one::CHEMBL85250

SMILES: CC(C)Oc1cccc(c1)-n1c(\C=C\c2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O

InChI Key: InChIKey=PMFMPPIYERXQGF-JLHYYAGUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (MOUSE)	BDBM50006836 (2-[2-(5-Bromo-1H-indol-3-yl)-vinyl]-3-(3-isopropox...) Show SMILES CC(C)Oc1cccc(c1)-n1c(\C=C\c2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C27H22BrN3O2/c1-17(2)33-21-7-5-6-20(15-21)31-26(30-25-9-4-3-8-22(25)27(31)32)13-10-18-16-29-24-12-11-19(28)14-23(18)24/h3-17,29H,1-2H3/b13-10+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Evaluated for inhibition of [125I]-CCK-8S binding to cholecystokinin CCK-B receptor from mouse brain membranes at a concentration of 10 microM (in vi...				J Med Chem 35: 2534-42 (1992) BindingDB Entry DOI: 10.7270/Q2JM28MX
					More data for this Ligand-Target Pair