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BDBM50006870 CHEMBL3237230

SMILES: Cc1c(-c2ccc(=O)n(Cc3ccccc3)c2)c2cc(F)ccc2n1CC(O)=O

InChI Key: InChIKey=PHDYMEBDGLWRBH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006870   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50006870
PNG
(CHEMBL3237230)
Show SMILES Cc1c(-c2ccc(=O)n(Cc3ccccc3)c2)c2cc(F)ccc2n1CC(O)=O
Show InChI InChI=1S/C23H19FN2O3/c1-15-23(19-11-18(24)8-9-20(19)26(15)14-22(28)29)17-7-10-21(27)25(13-17)12-16-5-3-2-4-6-16/h2-11,13H,12,14H2,1H3,(H,28,29)
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Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CRTh2 expressed in CHO-K1 cells by cAMP TR FRET assay


J Med Chem 57: 1299-322 (2014)


Article DOI: 10.1021/jm401509e
BindingDB Entry DOI: 10.7270/Q21V5GGH
More data for this
Ligand-Target Pair