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BDBM50006893 CHEMBL3236956

SMILES: Cc1c(Cc2ccc(=O)n(Cc3c(F)cccc3F)n2)c2cc(F)ccc2n1CC(O)=O

InChI Key: InChIKey=CRVCRSDHYHVWKE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006893   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50006893
PNG
(CHEMBL3236956)
Show SMILES Cc1c(Cc2ccc(=O)n(Cc3c(F)cccc3F)n2)c2cc(F)ccc2n1CC(O)=O
Show InChI InChI=1S/C23H18F3N3O3/c1-13-16(17-9-14(24)5-7-21(17)28(13)12-23(31)32)10-15-6-8-22(30)29(27-15)11-18-19(25)3-2-4-20(18)26/h2-9H,10-12H2,1H3,(H,31,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CRTh2 expressed in CHO-K1 cells by cAMP TR FRET assay


J Med Chem 57: 1299-322 (2014)


Article DOI: 10.1021/jm401509e
BindingDB Entry DOI: 10.7270/Q21V5GGH
More data for this
Ligand-Target Pair