BDBM50006935 CHEMBL3237246

SMILES: CCC(=O)C1=C(O)C(=O)N(CCc2c[nH]c3ccccc23)C1c1ccc(cc1)C(=O)OC

InChI Key: InChIKey=DWSNQTNHVPPDNE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50006935 (CHEMBL3237246) Show SMILES CCC(=O)C1=C(O)C(=O)N(CCc2c[nH]c3ccccc23)C1c1ccc(cc1)C(=O)OC |c:4| Show InChI InChI=1S/C25H24N2O5/c1-3-20(28)21-22(15-8-10-16(11-9-15)25(31)32-2)27(24(30)23(21)29)13-12-17-14-26-19-7-5-4-6-18(17)19/h4-11,14,22,26,29H,3,12-13H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...				J Med Chem 57: 2334-56 (2014) Article DOI: 10.1021/jm401695d BindingDB Entry DOI: 10.7270/Q2SB4786
					More data for this Ligand-Target Pair