BDBM50006995 CHEMBL3237276

SMILES: COC(=O)c1ccc(C2N(CCc3c[nH]c4ccccc34)C(=O)C(O)=C2C(C)=O)c(OC)c1

InChI Key: InChIKey=NVXAKINZGSWVSQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50006995 (CHEMBL3237276) Show SMILES COC(=O)c1ccc(C2N(CCc3c[nH]c4ccccc34)C(=O)C(O)=C2C(C)=O)c(OC)c1 |c:26| Show InChI InChI=1S/C25H24N2O6/c1-14(28)21-22(18-9-8-15(25(31)33-3)12-20(18)32-2)27(24(30)23(21)29)11-10-16-13-26-19-7-5-4-6-17(16)19/h4-9,12-13,22,26,29H,10-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...				J Med Chem 57: 2334-56 (2014) Article DOI: 10.1021/jm401695d BindingDB Entry DOI: 10.7270/Q2SB4786
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