BDBM50007021 CHEMBL3237300

SMILES: COC(=O)c1ccc(cc1)C1N(CCc2c[nH]c3ccccc23)C(=O)C(OC(C)=O)=C1C(C)=O

InChI Key: InChIKey=MJOGPIWBJPURCJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50007021 (CHEMBL3237300) Show SMILES COC(=O)c1ccc(cc1)C1N(CCc2c[nH]c3ccccc23)C(=O)C(OC(C)=O)=C1C(C)=O |c:32| Show InChI InChI=1S/C26H24N2O6/c1-15(29)22-23(17-8-10-18(11-9-17)26(32)33-3)28(25(31)24(22)34-16(2)30)13-12-19-14-27-21-7-5-4-6-20(19)21/h4-11,14,23,27H,12-13H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...				J Med Chem 57: 2334-56 (2014) Article DOI: 10.1021/jm401695d BindingDB Entry DOI: 10.7270/Q2SB4786
					More data for this Ligand-Target Pair