BDBM50007183 4-Hydroxy-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-benzamide::CHEMBL27377

SMILES: COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(O)cc2)CC1

InChI Key: InChIKey=YSJVPVOMUFQUSU-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007183 (4-Hydroxy-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-y...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(O)cc2)CC1 Show InChI InChI=1S/C22H29N3O3/c1-28-21-7-3-2-6-20(21)25-16-14-24(15-17-25)13-5-4-12-23-22(27)18-8-10-19(26)11-9-18/h2-3,6-11,26H,4-5,12-17H2,1H3,(H,23,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor of rat hippocampus using [3H]-8-hydroxy-2-(di-n-propylamine) tetralin (8-OH-DPAT) as a radio...				J Med Chem 34: 2633-8 (1991) BindingDB Entry DOI: 10.7270/Q2833R0C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50007183 (4-Hydroxy-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-y...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(O)cc2)CC1 Show InChI InChI=1S/C22H29N3O3/c1-28-21-7-3-2-6-20(21)25-16-14-24(15-17-25)13-5-4-12-23-22(27)18-8-10-19(26)11-9-18/h2-3,6-11,26H,4-5,12-17H2,1H3,(H,23,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Lausanne Curated by ChEMBL					Assay Description Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement				J Med Chem 39: 126-34 (1996) Article DOI: 10.1021/jm950410b BindingDB Entry DOI: 10.7270/Q2VX0K7V
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50007183 (4-Hydroxy-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-y...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(O)cc2)CC1 Show InChI InChI=1S/C22H29N3O3/c1-28-21-7-3-2-6-20(21)25-16-14-24(15-17-25)13-5-4-12-23-22(27)18-8-10-19(26)11-9-18/h2-3,6-11,26H,4-5,12-17H2,1H3,(H,23,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor of rat frontal cortex using [3H]- WB- 4101 as a radioligand				J Med Chem 34: 2633-8 (1991) BindingDB Entry DOI: 10.7270/Q2833R0C
					More data for this Ligand-Target Pair