BDBM50007234 7-Fluoro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one::CHEMBL323071

SMILES: Fc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key: InChIKey=XTXHKKBSLRGOJD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50007234 (7-Fluoro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one ...) Show SMILES Fc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C10H6FN3O/c11-6-1-2-7-5(3-6)4-8-9(12-7)14-10(15)13-8/h1-4H,(H2,12,13,14,15)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of hydrolysis of c-AMP phosphodiesterase in human platelets				J Med Chem 34: 2906-16 (1991) BindingDB Entry DOI: 10.7270/Q20P0Z03
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50007234 (7-Fluoro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one ...) Show SMILES Fc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C10H6FN3O/c11-6-1-2-7-5(3-6)4-8-9(12-7)14-10(15)13-8/h1-4H,(H2,12,13,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of cGMP hydrolysis by human platelet phosphodiesterase				J Med Chem 34: 2906-16 (1991) BindingDB Entry DOI: 10.7270/Q20P0Z03
					More data for this Ligand-Target Pair