BDBM50007378 CHEMBL107543::N-Methyl-N-(2-methyl-1-pyrrolidin-1-ylmethyl-propyl)-2-phenoxy-acetamide

SMILES: CC(C)[C@@H](CN1CCCC1)N(C)C(=O)COc1ccccc1

InChI Key: InChIKey=IOIKZAWJOSFDMX-QGZVFWFLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007378 (CHEMBL107543 | N-Methyl-N-(2-methyl-1-pyrrolidin-1...) Show SMILES CC(C)[C@@H](CN1CCCC1)N(C)C(=O)COc1ccccc1 Show InChI InChI=1S/C18H28N2O2/c1-15(2)17(13-20-11-7-8-12-20)19(3)18(21)14-22-16-9-5-4-6-10-16/h4-6,9-10,15,17H,7-8,11-14H2,1-3H3/t17-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligand				J Med Chem 34: 3149-58 (1991) BindingDB Entry DOI: 10.7270/Q2028S53
					More data for this Ligand-Target Pair