BDBM50007478 4-(3-tert-Butylamino-2-hydroxy-propoxy)-5-fluoro-benzene-1,2-diol::CHEMBL10494
SMILES: CC(C)(C)NCC(O)COc1cc(O)c(O)cc1F
InChI Key: InChIKey=JEUSMJOCKAGUHH-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50007478 (4-(3-tert-Butylamino-2-hydroxy-propoxy)-5-fluoro-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of binding of [3H]-dihydroalprenolol from beta-1 adrenergic receptor of rat cerebral cortical membranes | J Med Chem 34: 1063-8 (1991) BindingDB Entry DOI: 10.7270/Q2765D9R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (GUINEA PIG) | BDBM50007478 (4-(3-tert-Butylamino-2-hydroxy-propoxy)-5-fluoro-b...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 175 | n/a | n/a | n/a | n/a |
National Institute of Diabetes Curated by ChEMBL | Assay Description Agonistic activity (beta-1 adrenergic receptor) for the percent maximal increase in contraction rate of isolated guinea pig atria | J Med Chem 34: 1063-8 (1991) BindingDB Entry DOI: 10.7270/Q2765D9R | |||||||||||
More data for this Ligand-Target Pair |