BDBM50007540 CHEMBL279907::[3-(4-Chloro-phenyl)-3-(5-chloro-pyridin-2-yl)-propyl]-dimethyl-amine

SMILES: CN(C)CCC(c1ccc(Cl)cc1)c1ccc(Cl)cn1

InChI Key: InChIKey=WSNDRKOLHPSTJY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50007540 (CHEMBL279907 | [3-(4-Chloro-phenyl)-3-(5-chloro-py...) Show SMILES CN(C)CCC(c1ccc(Cl)cc1)c1ccc(Cl)cn1 Show InChI InChI=1S/C16H18Cl2N2/c1-20(2)10-9-15(12-3-5-13(17)6-4-12)16-8-7-14(18)11-19-16/h3-8,11,15H,9-10H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
A. H. Robins Company, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-mepyramine binding to the Histamine H1 receptor in guinea pig cortex				J Med Chem 34: 1314-28 (1991) BindingDB Entry DOI: 10.7270/Q23F4NMG
					More data for this Ligand-Target Pair