BDBM50007759 CHEMBL3233769

SMILES: Fc1ccc(Nc2ncnc3sc(NC(=O)OCC=C)cc23)cc1Cl

InChI Key: InChIKey=LINHGPOBLOFLBF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50007759 (CHEMBL3233769) Show SMILES Fc1ccc(Nc2ncnc3sc(NC(=O)OCC=C)cc23)cc1Cl Show InChI InChI=1S/C16H12ClFN4O2S/c1-2-5-24-16(23)22-13-7-10-14(19-8-20-15(10)25-13)21-9-3-4-12(18)11(17)6-9/h2-4,6-8H,1,5H2,(H,22,23)(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of wild type EGFR domain (unknown origin) expressed in baculovirus expression system using Poly(Glu:Tyr)4:1 substrate after 60 mins by ELI...				Bioorg Med Chem 22: 2366-78 (2014) Article DOI: 10.1016/j.bmc.2014.01.035 BindingDB Entry DOI: 10.7270/Q2QC051F
					More data for this Ligand-Target Pair