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SMILES: CN1[C@@H]2CCC1C([C@H](C2)OC(=O)c1ccccc1)C(=O)OCc1ccccc1

InChI Key: InChIKey=CODRVQGKDHKTDZ-OSIBBQKWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008050   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent dopamine transporter


(Rattus norvegicus (rat))		BDBM50008050
PNG
(3-Benzoyloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2...)
Show SMILES CN1[C@@H]2CCC1C([C@H](C2)OC(=O)c1ccccc1)C(=O)OCc1ccccc1 |TLB:18:6:1:4.3,9:7:1:4.3,0:1:6.7.8:4.3|
Show InChI InChI=1S/C23H25NO4/c1-24-18-12-13-19(24)21(23(26)27-15-16-8-4-2-5-9-16)20(14-18)28-22(25)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19?,20+,21?/m1/s1
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 257n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]3-beta-(p-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to Dopamine transporter in rat striatal membranes.

J Med Chem 35: 135-40 (1992)


BindingDB Entry DOI: 10.7270/Q2FQ9X7M
More data for this
Ligand-Target Pair