BDBM50008299 6-(3,5-Dichloro-phenylsulfanyl)-5-ethyl-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL429778

SMILES: CCc1c(Sc2cc(Cl)cc(Cl)c2)n(COCCO)c(=O)[nH]c1=O

InChI Key: InChIKey=MHEVAGSEJUCLJG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50008299 (6-(3,5-Dichloro-phenylsulfanyl)-5-ethyl-1-(2-hydro...) Show SMILES CCc1c(Sc2cc(Cl)cc(Cl)c2)n(COCCO)c(=O)[nH]c1=O Show InChI InChI=1S/C15H16Cl2N2O4S/c1-2-12-13(21)18-15(22)19(8-23-4-3-20)14(12)24-11-6-9(16)5-10(17)7-11/h5-7,20H,2-4,8H2,1H3,(H,18,21,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Inhibitory concentration against HIV-1 reverse transcriptase				J Med Chem 40: 4257-64 (1998) Article DOI: 10.1021/jm970110p BindingDB Entry DOI: 10.7270/Q2WS8SC3
					More data for this Ligand-Target Pair