BDBM50008431 3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-butyramide::CHEMBL309130

SMILES: CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1

InChI Key: InChIKey=WABAJXKDQWZIOJ-KGLIPLIRSA-N

Data: 6 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50008431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine aminopeptidase (Homo sapiens (Human))	BDBM50008431 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...) Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibitory activity against Leucine aminopeptidase				J Med Chem 31: 2193-9 (1988) BindingDB Entry DOI: 10.7270/Q2Z038RM
					More data for this Ligand-Target Pair
Aspartyl aminopeptidase (Homo sapiens (Human))	BDBM50008431 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...) Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Compound was tested for binding affinity towards cytosolic aminopeptidase				J Med Chem 35: 451-6 (1992) BindingDB Entry DOI: 10.7270/Q2CR5SBH
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50008431 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...) Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Compound was tested for binding affinity towards microsomal aminopeptidase				J Med Chem 35: 451-6 (1992) BindingDB Entry DOI: 10.7270/Q2CR5SBH
					More data for this Ligand-Target Pair				3D Structure (docked)
Aminopeptidase N (Sus scrofa (Pig))	BDBM50008431 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...) Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibitory activity against Aminopeptidase M				J Med Chem 31: 2193-9 (1988) BindingDB Entry DOI: 10.7270/Q2Z038RM
					More data for this Ligand-Target Pair
Aminopeptidase B (Homo sapiens (Human))	BDBM50008431 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...) Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Compound was tested for binding affinity towards arginyl aminopeptidase				J Med Chem 35: 451-6 (1992) BindingDB Entry DOI: 10.7270/Q2CR5SBH
					More data for this Ligand-Target Pair
Aminopeptidase B (Rattus norvegicus)	BDBM50008431 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...) Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin Curated by ChEMBL					Assay Description Inhibitory activity against aminopeptidase B				J Med Chem 31: 2193-9 (1988) BindingDB Entry DOI: 10.7270/Q2Z038RM
					More data for this Ligand-Target Pair
Aminopeptidase B (Rattus norvegicus)	BDBM50008431 (3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...) Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1 Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat liver aminopeptidase B using 0.2 mM L-leucine-beta-naphthylamide by colorimetry				J Med Chem 20: 510-5 (1977) BindingDB Entry DOI: 10.7270/Q29W0H11
					More data for this Ligand-Target Pair