BDBM50008956 2,6-Diisopropyl-4-[2-(5-methyl-1H-pyrazol-3-yl)-vinyl]-phenol::CHEMBL150804

SMILES: CC(C)c1cc(C=Cc2cc(C)n[nH]2)cc(C(C)C)c1O

InChI Key: InChIKey=VTXYVNRRDQIDHX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (RAT)	BDBM50008956 (2,6-Diisopropyl-4-[2-(5-methyl-1H-pyrazol-3-yl)-vi...) Show SMILES CC(C)c1cc(C=Cc2cc(C)n[nH]2)cc(C(C)C)c1O |w:7.7| Show InChI InChI=1S/C18H24N2O/c1-11(2)16-9-14(10-17(12(3)4)18(16)21)6-7-15-8-13(5)19-20-15/h6-12,21H,1-5H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against cyclooxygenase in rat basophilic leukemia cells using prostaglandin G/H synthase assay				J Med Chem 34: 518-25 (1991) BindingDB Entry DOI: 10.7270/Q2ZG6R66
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50008956 (2,6-Diisopropyl-4-[2-(5-methyl-1H-pyrazol-3-yl)-vi...) Show SMILES CC(C)c1cc(C=Cc2cc(C)n[nH]2)cc(C(C)C)c1O |w:7.7| Show InChI InChI=1S/C18H24N2O/c1-11(2)16-9-14(10-17(12(3)4)18(16)21)6-7-15-8-13(5)19-20-15/h6-12,21H,1-5H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells				J Med Chem 34: 518-25 (1991) BindingDB Entry DOI: 10.7270/Q2ZG6R66
					More data for this Ligand-Target Pair