BDBM50009016 2-(4-Phenyl-butyl)-1,2-dihydro-indazol-3-one::CHEMBL269654::CHEMBL3144714

SMILES: O=c1n(CCCCc2ccccc2)[nH]c2ccccc12

InChI Key: InChIKey=VMGHZFARQGLROM-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50009016 (2-(4-Phenyl-butyl)-1,2-dihydro-indazol-3-one | CHE...) Show SMILES O=c1n(CCCCc2ccccc2)[nH]c2ccccc12 Show InChI InChI=1S/C17H18N2O/c20-17-15-11-4-5-12-16(15)18-19(17)13-7-6-10-14-8-2-1-3-9-14/h1-5,8-9,11-12,18H,6-7,10,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description In vitro inhibition of LTB4 production was measured in rat blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50009016 (2-(4-Phenyl-butyl)-1,2-dihydro-indazol-3-one | CHE...) Show SMILES O=c1n(CCCCc2ccccc2)[nH]c2ccccc12 Show InChI InChI=1S/C17H18N2O/c20-17-15-11-4-5-12-16(15)18-19(17)13-7-6-10-14-8-2-1-3-9-14/h1-5,8-9,11-12,18H,6-7,10,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>100	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description Ex vivo inhibition of LTB4 production was measured in dog blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair
Cyclooxygenase (RAT)	BDBM50009016 (2-(4-Phenyl-butyl)-1,2-dihydro-indazol-3-one | CHE...) Show SMILES O=c1n(CCCCc2ccccc2)[nH]c2ccccc12 Show InChI InChI=1S/C17H18N2O/c20-17-15-11-4-5-12-16(15)18-19(17)13-7-6-10-14-8-2-1-3-9-14/h1-5,8-9,11-12,18H,6-7,10,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharma Curated by ChEMBL					Assay Description In vitro inhibition of PGE-2 production was measured in rat blood				J Med Chem 34: 1028-36 (1991) BindingDB Entry DOI: 10.7270/Q28G8MXH
					More data for this Ligand-Target Pair