BDBM50009097 CHEMBL3238298

SMILES: CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)Nc1ccccc1)S(=O)(=O)c1ccc(N)nc1

InChI Key: InChIKey=YVEKHWIBGXZBGG-NRFANRHFSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase regulatory protein (Mus musculus)	BDBM50009097 (CHEMBL3238298) Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)Nc1ccccc1)S(=O)(=O)c1ccc(N)nc1 |r| Show InChI InChI=1S/C24H25N5O4S2/c1-2-6-21-18-28(35(32,33)23-13-14-24(25)26-17-23)15-16-29(21)20-9-11-22(12-10-20)34(30,31)27-19-7-4-3-5-8-19/h3-5,7-14,17,21,27H,15-16,18H2,1H3,(H2,25,26)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...				J Med Chem 57: 3094-116 (2014) Article DOI: 10.1021/jm5000497 BindingDB Entry DOI: 10.7270/Q2V126BF
					More data for this Ligand-Target Pair
Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50009097 (CHEMBL3238298) Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)Nc1ccccc1)S(=O)(=O)c1ccc(N)nc1 |r| Show InChI InChI=1S/C24H25N5O4S2/c1-2-6-21-18-28(35(32,33)23-13-14-24(25)26-17-23)15-16-29(21)20-9-11-22(12-10-20)34(30,31)27-19-7-4-3-5-8-19/h3-5,7-14,17,21,27H,15-16,18H2,1H3,(H2,25,26)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of biotin-tagged human GKRP/fluorescein-tagged GK interaction preincubated for 20 mins prior to GK addition measured after 2 to 4 hrs by A...				J Med Chem 57: 3094-116 (2014) Article DOI: 10.1021/jm5000497 BindingDB Entry DOI: 10.7270/Q2V126BF
					More data for this Ligand-Target Pair