BDBM50009565 CHEMBL312992::Dimethyl-{4-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenyl}-amine::Dimethyl-{4-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenyl}-amine

SMILES: COc1cc(\C=C/c2ccc(cc2)N(C)C)cc(OC)c1OC

InChI Key: InChIKey=PHDDAWSHQWUPPP-SREVYHEPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50009565 (CHEMBL312992 | Dimethyl-{4-[(Z)-2-(3,4,5-trimethox...) Show SMILES COc1cc(\C=C/c2ccc(cc2)N(C)C)cc(OC)c1OC Show InChI InChI=1S/C19H23NO3/c1-20(2)16-10-8-14(9-11-16)6-7-15-12-17(21-3)19(23-5)18(13-15)22-4/h6-13H,1-5H3/b7-6-	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to inhibit Tubulin polymerization in Bovine brain				J Med Chem 34: 2579-88 (1991) BindingDB Entry DOI: 10.7270/Q2KW5J8Z
					More data for this Ligand-Target Pair
Tubulin (Sus scrofa (Pig))	BDBM50009565 (CHEMBL312992 | Dimethyl-{4-[(Z)-2-(3,4,5-trimethox...) Show SMILES COc1cc(\C=C/c2ccc(cc2)N(C)C)cc(OC)c1OC Show InChI InChI=1S/C19H23NO3/c1-20(2)16-10-8-14(9-11-16)6-7-15-12-17(21-3)19(23-5)18(13-15)22-4/h6-13H,1-5H3/b7-6-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit polymerization of tubulin				Bioorg Med Chem Lett 11: 871-4 (2001) BindingDB Entry DOI: 10.7270/Q25X2867
					More data for this Ligand-Target Pair