BDBM50009632 CHEMBL3234857

SMILES: C[C@@H](N1C(=O)O[C@@](Cc2ccccc2)(C1=O)c1nnc(o1)-c1ccc(Cl)c(Cl)c1)c1ccccc1

InChI Key: InChIKey=NVXYXJJXVNHKTF-AKJBCIBTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50009632 (CHEMBL3234857) Show SMILES C[C@@H](N1C(=O)O[C@@](Cc2ccccc2)(C1=O)c1nnc(o1)-c1ccc(Cl)c(Cl)c1)c1ccccc1 |r| Show InChI InChI=1S/C26H19Cl2N3O4/c1-16(18-10-6-3-7-11-18)31-24(32)26(35-25(31)33,15-17-8-4-2-5-9-17)23-30-29-22(34-23)19-12-13-20(27)21(28)14-19/h2-14,16H,15H2,1H3/t16-,26-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assay				Bioorg Med Chem Lett 24: 1681-4 (2014) Article DOI: 10.1016/j.bmcl.2014.02.057 BindingDB Entry DOI: 10.7270/Q2N87C9H
					More data for this Ligand-Target Pair