BDBM50009684 CHEMBL301574::Cyclopentyl-(9-ethyl-9H-purin-6-yl)-amine::N-cyclopentyl-9-ethyl-9H-purin-6-amine

SMILES: CCn1cnc2c(NC3CCCC3)ncnc12

InChI Key: InChIKey=CDVHQRUOORNLKE-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50009684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50009684 (CHEMBL301574 | Cyclopentyl-(9-ethyl-9H-purin-6-yl)...) Show SMILES CCn1cnc2c(NC3CCCC3)ncnc12 Show InChI InChI=1S/C12H17N5/c1-2-17-8-15-10-11(13-7-14-12(10)17)16-9-5-3-4-6-9/h7-9H,2-6H2,1H3,(H,13,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor from rat brain.				J Med Chem 38: 1720-35 (1995) BindingDB Entry DOI: 10.7270/Q21Z453H
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50009684 (CHEMBL301574 | Cyclopentyl-(9-ethyl-9H-purin-6-yl)...) Show SMILES CCn1cnc2c(NC3CCCC3)ncnc12 Show InChI InChI=1S/C12H17N5/c1-2-17-8-15-10-11(13-7-14-12(10)17)16-9-5-3-4-6-9/h7-9H,2-6H2,1H3,(H,13,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in rat cortex by using [3H]- PIA as a radioligand				J Med Chem 34: 2877-82 (1991) BindingDB Entry DOI: 10.7270/Q2Q81DQN
					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50009684 (CHEMBL301574 | Cyclopentyl-(9-ethyl-9H-purin-6-yl)...) Show SMILES CCn1cnc2c(NC3CCCC3)ncnc12 Show InChI InChI=1S/C12H17N5/c1-2-17-8-15-10-11(13-7-14-12(10)17)16-9-5-3-4-6-9/h7-9H,2-6H2,1H3,(H,13,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Tested for inhibition of rat PC12 adenylate cyclase stimulation by using NECA as a radioligand				J Med Chem 34: 2877-82 (1991) BindingDB Entry DOI: 10.7270/Q2Q81DQN
					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50009684 (CHEMBL301574 | Cyclopentyl-(9-ethyl-9H-purin-6-yl)...) Show SMILES CCn1cnc2c(NC3CCCC3)ncnc12 Show InChI InChI=1S/C12H17N5/c1-2-17-8-15-10-11(13-7-14-12(10)17)16-9-5-3-4-6-9/h7-9H,2-6H2,1H3,(H,13,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Binding affinity against adenosine A2 receptor in rat striatum by using [3H]NECA as a radioligand				J Med Chem 34: 2877-82 (1991) BindingDB Entry DOI: 10.7270/Q2Q81DQN
					More data for this Ligand-Target Pair
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50009684 (CHEMBL301574 | Cyclopentyl-(9-ethyl-9H-purin-6-yl)...) Show SMILES CCn1cnc2c(NC3CCCC3)ncnc12 Show InChI InChI=1S/C12H17N5/c1-2-17-8-15-10-11(13-7-14-12(10)17)16-9-5-3-4-6-9/h7-9H,2-6H2,1H3,(H,13,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against adenosine A2A receptor from rat brain.				J Med Chem 38: 1720-35 (1995) BindingDB Entry DOI: 10.7270/Q21Z453H
					More data for this Ligand-Target Pair