BDBM50010032 1-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-1H-benzo[cd]indol-2-one::CHEMBL442185

SMILES: O=C1N(CCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23

InChI Key: InChIKey=RWOFMBJYEBXDKZ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50010032 (1-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl...) Show SMILES O=C1N(CCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23 |c:9| Show InChI InChI=1S/C25H24N2O/c28-25-22-11-4-9-21-10-5-12-23(24(21)22)27(25)16-6-15-26-17-13-20(14-18-26)19-7-2-1-3-8-19/h1-5,7-13H,6,14-18H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description The concentration required to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)				J Med Chem 34: 2477-83 (1991) BindingDB Entry DOI: 10.7270/Q2R78FT1
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50010032 (1-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl...) Show SMILES O=C1N(CCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23 |c:9| Show InChI InChI=1S/C25H24N2O/c28-25-22-11-4-9-21-10-5-12-23(24(21)22)27(25)16-6-15-26-17-13-20(14-18-26)19-7-2-1-3-8-19/h1-5,7-13H,6,14-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)				J Med Chem 34: 2477-83 (1991) BindingDB Entry DOI: 10.7270/Q2R78FT1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010032 (1-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl...) Show SMILES O=C1N(CCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23 |c:9| Show InChI InChI=1S/C25H24N2O/c28-25-22-11-4-9-21-10-5-12-23(24(21)22)27(25)16-6-15-26-17-13-20(14-18-26)19-7-2-1-3-8-19/h1-5,7-13H,6,14-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)				J Med Chem 34: 2477-83 (1991) BindingDB Entry DOI: 10.7270/Q2R78FT1
					More data for this Ligand-Target Pair