BDBM50010036 10-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-10H-9-thia-10-aza-phenanthrene 9,9-dioxide::CHEMBL83664

SMILES: O=S1(=O)N(CCCN2CCC(=CC2)c2ccccc2)c2ccccc2-c2ccccc12

InChI Key: InChIKey=CUSNRDWDRXFUFH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50010036 (10-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propy...) Show SMILES O=S1(=O)N(CCCN2CCC(=CC2)c2ccccc2)c2ccccc2-c2ccccc12 |c:10| Show InChI InChI=1S/C26H26N2O2S/c29-31(30)26-14-7-5-12-24(26)23-11-4-6-13-25(23)28(31)18-8-17-27-19-15-22(16-20-27)21-9-2-1-3-10-21/h1-7,9-15H,8,16-20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)				J Med Chem 34: 2477-83 (1991) BindingDB Entry DOI: 10.7270/Q2R78FT1
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50010036 (10-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propy...) Show SMILES O=S1(=O)N(CCCN2CCC(=CC2)c2ccccc2)c2ccccc2-c2ccccc12 |c:10| Show InChI InChI=1S/C26H26N2O2S/c29-31(30)26-14-7-5-12-24(26)23-11-4-6-13-25(23)28(31)18-8-17-27-19-15-22(16-20-27)21-9-2-1-3-10-21/h1-7,9-15H,8,16-20H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description The concentration required to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)				J Med Chem 34: 2477-83 (1991) BindingDB Entry DOI: 10.7270/Q2R78FT1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010036 (10-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propy...) Show SMILES O=S1(=O)N(CCCN2CCC(=CC2)c2ccccc2)c2ccccc2-c2ccccc12 |c:10| Show InChI InChI=1S/C26H26N2O2S/c29-31(30)26-14-7-5-12-24(26)23-11-4-6-13-25(23)28(31)18-8-17-27-19-15-22(16-20-27)21-9-2-1-3-10-21/h1-7,9-15H,8,16-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)				J Med Chem 34: 2477-83 (1991) BindingDB Entry DOI: 10.7270/Q2R78FT1
					More data for this Ligand-Target Pair