BDBM50010050 CHEMBL309660::N-Phenyl-N-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-benzenesulfonamide

SMILES: O=S(=O)(N(CCCN1CCC(=CC1)c1ccccc1)c1ccccc1)c1ccccc1

InChI Key: InChIKey=QWVPSLXKIGGBPP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50010050 (CHEMBL309660 | N-Phenyl-N-[3-(4-phenyl-3,6-dihydro...) Show SMILES O=S(=O)(N(CCCN1CCC(=CC1)c1ccccc1)c1ccccc1)c1ccccc1 |c:10| Show InChI InChI=1S/C26H28N2O2S/c29-31(30,26-15-8-3-9-16-26)28(25-13-6-2-7-14-25)20-10-19-27-21-17-24(18-22-27)23-11-4-1-5-12-23/h1-9,11-17H,10,18-22H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)				J Med Chem 34: 2477-83 (1991) BindingDB Entry DOI: 10.7270/Q2R78FT1
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50010050 (CHEMBL309660 | N-Phenyl-N-[3-(4-phenyl-3,6-dihydro...) Show SMILES O=S(=O)(N(CCCN1CCC(=CC1)c1ccccc1)c1ccccc1)c1ccccc1 |c:10| Show InChI InChI=1S/C26H28N2O2S/c29-31(30,26-15-8-3-9-16-26)28(25-13-6-2-7-14-25)20-10-19-27-21-17-24(18-22-27)23-11-4-1-5-12-23/h1-9,11-17H,10,18-22H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description The concentration required to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)				J Med Chem 34: 2477-83 (1991) BindingDB Entry DOI: 10.7270/Q2R78FT1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010050 (CHEMBL309660 | N-Phenyl-N-[3-(4-phenyl-3,6-dihydro...) Show SMILES O=S(=O)(N(CCCN1CCC(=CC1)c1ccccc1)c1ccccc1)c1ccccc1 |c:10| Show InChI InChI=1S/C26H28N2O2S/c29-31(30,26-15-8-3-9-16-26)28(25-13-6-2-7-14-25)20-10-19-27-21-17-24(18-22-27)23-11-4-1-5-12-23/h1-9,11-17H,10,18-22H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)				J Med Chem 34: 2477-83 (1991) BindingDB Entry DOI: 10.7270/Q2R78FT1
					More data for this Ligand-Target Pair