BDBM50010315 CHEMBL3251363
SMILES: Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c(Sc3ccccc3)nc12
InChI Key: InChIKey=DCARDSHKJRCYNY-SDBHATRESA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenylate kinase 2 (Rattus norvegicus) | BDBM50010315 (CHEMBL3251363) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of Sprague-Dawley rat liver adenylate kinase 2 by Lineweaver-Burk plot analysis | J Med Chem 22: 1529-32 (1980) BindingDB Entry DOI: 10.7270/Q2JD4Z9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate kinase 3 alpha like 1 (Rattus norvegicus) | BDBM50010315 (CHEMBL3251363) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive binding inhibition constant of rat Adenylate kinase III was determined | J Med Chem 25: 638-44 (1982) BindingDB Entry DOI: 10.7270/Q2MG7Q28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate kinase 2 (Rattus norvegicus) | BDBM50010315 (CHEMBL3251363) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive binding inhibition constant (Ki) of rat adenylate kinase (AK II) isozymes was determined | J Med Chem 25: 638-44 (1982) BindingDB Entry DOI: 10.7270/Q2MG7Q28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate kinase 3 alpha like 1 (Rattus norvegicus) | BDBM50010315 (CHEMBL3251363) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Competitive inhibition of Sprague-Dawley rat liver adenylate kinase 3 by Lineweaver-Burk plot analysis | J Med Chem 22: 1529-32 (1980) BindingDB Entry DOI: 10.7270/Q2JD4Z9V | |||||||||||
More data for this Ligand-Target Pair |