BDBM50010506 CHEMBL3264373

SMILES: Cc1cc(C)cc(c1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1

InChI Key: InChIKey=QRQDRRFEPQKDRO-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010506   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010506 (CHEMBL3264373) Show SMILES Cc1cc(C)cc(c1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C23H27N5O/c1-17-13-18(2)15-19(14-17)28-11-9-27(10-12-28)8-7-24-23(29)22-16-25-20-5-3-4-6-21(20)26-22/h3-6,13-16H,7-12H2,1-2H3,(H,24,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50010506 (CHEMBL3264373) Show SMILES Cc1cc(C)cc(c1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C23H27N5O/c1-17-13-18(2)15-19(14-17)28-11-9-27(10-12-28)8-7-24-23(29)22-16-25-20-5-3-4-6-21(20)26-22/h3-6,13-16H,7-12H2,1-2H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	383	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Agonist activity at Wistar rat brain 5HT1A receptor assessed as inhibition of firing rate of dorsal raphe nucleus by electrophysiological analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair