BDBM50010507 CHEMBL3264374

SMILES: Cc1cc(C)cc(c1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1

InChI Key: InChIKey=WWRNBRQXALOFCO-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010507 (CHEMBL3264374) Show SMILES Cc1cc(C)cc(c1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 |t:9| Show InChI InChI=1S/C24H26N4O/c1-17-13-18(2)15-20(14-17)19-7-10-28(11-8-19)12-9-25-24(29)23-16-26-21-5-3-4-6-22(21)27-23/h3-7,13-16H,8-12H2,1-2H3,(H,25,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50010507 (CHEMBL3264374) Show SMILES Cc1cc(C)cc(c1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 |t:9| Show InChI InChI=1S/C24H26N4O/c1-17-13-18(2)15-20(14-17)19-7-10-28(11-8-19)12-9-25-24(29)23-16-26-21-5-3-4-6-22(21)27-23/h3-7,13-16H,8-12H2,1-2H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Agonist activity at Wistar rat brain 5HT1A receptor assessed as inhibition of firing rate of dorsal raphe nucleus by electrophysiological analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair