BDBM50010794 CHEMBL312318::N,N'-Bis-(2,6-dimethyl-phenyl)-guanidine

SMILES: Cc1cccc(C)c1NC(N)=Nc1c(C)cccc1C

InChI Key: InChIKey=GKFJJGGJSQMXIU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010794   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50010794 (CHEMBL312318 | N,N'-Bis-(2,6-dimethyl-phenyl)-guan...) Show SMILES Cc1cccc(C)c1NC(N)=Nc1c(C)cccc1C |w:11.12| Show InChI InChI=1S/C17H21N3/c1-11-7-5-8-12(2)15(11)19-17(18)20-16-13(3)9-6-10-14(16)4/h5-10H,1-4H3,(H3,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description In vitro inhibitory activity against [3H]- (+)-3-PPP binding to Sigma opioid receptor in guinea pig brain membrane homogenates				J Med Chem 33: 2421-9 (1990) BindingDB Entry DOI: 10.7270/Q25Q4WQ3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50010794 (CHEMBL312318 | N,N'-Bis-(2,6-dimethyl-phenyl)-guan...) Show SMILES Cc1cccc(C)c1NC(N)=Nc1c(C)cccc1C |w:11.12| Show InChI InChI=1S/C17H21N3/c1-11-7-5-8-12(2)15(11)19-17(18)20-16-13(3)9-6-10-14(16)4/h5-10H,1-4H3,(H3,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description In vitro inhibitory activity against [3H]- (+)-3-PPP binding to sigma receptor in guinea pig brain membrane homogenates				J Med Chem 33: 2421-9 (1990) BindingDB Entry DOI: 10.7270/Q25Q4WQ3
					More data for this Ligand-Target Pair