BDBM50011027 2-Ethyl-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-4,5-diphenyl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL420337

SMILES: CCOC(=O)c1c(CC)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1-c1ccccc1)-c1ccccc1

InChI Key: InChIKey=NSRNYHXNPLWZPI-FGZHOGPDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HMG-CoA reductase (Rattus norvegicus (rat))	BDBM50011027 (2-Ethyl-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-y...) Show SMILES CCOC(=O)c1c(CC)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C28H31NO5/c1-3-23-26(28(32)33-4-2)25(19-11-7-5-8-12-19)27(20-13-9-6-10-14-20)29(23)16-15-22-17-21(30)18-24(31)34-22/h5-14,21-22,30H,3-4,15-18H2,1-2H3/t21-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of HMG-CoA reductase activity in partially purified rat liver				J Med Chem 34: 357-66 (1991) BindingDB Entry DOI: 10.7270/Q2NV9H6F
					More data for this Ligand-Target Pair