BindingDB PrimarySearch

BDBM50011256 (+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride::(+/-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride::(-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol::(-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride::7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrochloride::CHEMBL14708::CHEMBL544668

SMILES: CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C

InChI Key: InChIKey=YRGIQICNKWCKCO-CJNGLKHVSA-N

Data: 2 KI 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50011256
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	656	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	486	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	774	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	486	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	774	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair