BindingDB PrimarySearch

BDBM50011265 (+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide::(+/-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol::(+/-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide::(-)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide::7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide::CHEMBL14791::CHEMBL544899

SMILES: CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C

InChI Key: InChIKey=YRGIQICNKWCKCO-BBRMVZONSA-N

Data: 2 KI 6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50011265
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description In vitro Inhibitory activity tested at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
University of Uppsala Curated by ChEMBL					Assay Description Inhibitory activity tested in vitro at 5-hydroxytryptamine 1A receptor binding site in rat				J Med Chem 31: 1130-40 (1988) BindingDB Entry DOI: 10.7270/Q23J3DJB
University of Uppsala Curated by ChEMBL					More data for this Ligand-Target Pair