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SMILES: Nc1cccc(c1)-c1cnc(N)nc1

InChI Key: InChIKey=RGGDATRAQXMTDI-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011547   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase kinase 4


(Homo sapiens (Human))		BDBM50011547
PNG
(CHEMBL3262566)
Show SMILES Nc1cccc(c1)-c1cnc(N)nc1
Show InChI InChI=1S/C10H10N4/c11-9-3-1-2-7(4-9)8-5-13-10(12)14-6-8/h1-6H,11H2,(H2,12,13,14)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 1.75E+5n/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...

J Med Chem 57: 3484-93 (2014)


Article DOI: 10.1021/jm500155b
BindingDB Entry DOI: 10.7270/Q2M046ZR
More data for this
Ligand-Target Pair