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SMILES: CN(C)CCn1c2ccccc2n(CC#Cc2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)c1=O

InChI Key: InChIKey=QMULKKMSJZSCJB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011618   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011618
PNG
(1-{3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8...)
Show SMILES CN(C)CCn1c2ccccc2n(CC#Cc2cc3c(s2)-n2c(C)nnc2CN=C3c2ccccc2Cl)c1=O |c:31|
Show InChI InChI=1S/C29H26ClN7OS/c1-19-32-33-26-18-31-27(21-10-4-5-11-23(21)30)22-17-20(39-28(22)37(19)26)9-8-14-35-24-12-6-7-13-25(24)36(29(35)38)16-15-34(2)3/h4-7,10-13,17H,14-16,18H2,1-3H3
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n/an/a 30n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay

J Med Chem 34: 1209-21 (1991)


BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair