BDBM50011628 4-(2-Chloro-phenyl)-2-iodo-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene::CHEMBL20359

SMILES: Cc1nnc2CN=C(c3cc(I)sc3-n12)c1ccccc1Cl

InChI Key: InChIKey=KJZJHABCRCESGN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50011628 (4-(2-Chloro-phenyl)-2-iodo-9-methyl-6H-1-thia-5,7,...) Show SMILES Cc1nnc2CN=C(c3cc(I)sc3-n12)c1ccccc1Cl |c:6| Show InChI InChI=1S/C15H10ClIN4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)16)10-6-12(17)22-15(10)21(8)13/h2-6H,7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description PAF-antagonist activity determined in dog platelets by PAF-binding assay				J Med Chem 34: 1209-21 (1991) BindingDB Entry DOI: 10.7270/Q23X85M1
					More data for this Ligand-Target Pair
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50011628 (4-(2-Chloro-phenyl)-2-iodo-9-methyl-6H-1-thia-5,7,...) Show SMILES Cc1nnc2CN=C(c3cc(I)sc3-n12)c1ccccc1Cl |c:6| Show InChI InChI=1S/C15H10ClIN4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)16)10-6-12(17)22-15(10)21(8)13/h2-6H,7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.				J Med Chem 34: 1440-6 (1991) BindingDB Entry DOI: 10.7270/Q2BG2MZ9
					More data for this Ligand-Target Pair