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SMILES: Cc1nnc2CN=C(c3cc(sc3-n12)C#CCn1c2cc(Cl)ccc2c2ccc(Cl)cc2c1=O)c1ccccc1Cl

InChI Key: InChIKey=KVKMLKCPLXQHGB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011667   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011667
PNG
(3,8-Dichloro-5-{3-[4-(2-chloro-phenyl)-9-methyl-6H...)
Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C#CCn1c2cc(Cl)ccc2c2ccc(Cl)cc2c1=O)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C31H18Cl3N5OS/c1-17-36-37-28-16-35-29(23-6-2-3-7-26(23)34)25-15-20(41-31(25)39(17)28)5-4-12-38-27-14-19(33)9-11-22(27)21-10-8-18(32)13-24(21)30(38)40/h2-3,6-11,13-15H,12,16H2,1H3
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n/an/a 30n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
PAF-antagonist activity determined in dog platelets by PAF-binding assay

J Med Chem 34: 1209-21 (1991)


BindingDB Entry DOI: 10.7270/Q23X85M1
More data for this
Ligand-Target Pair