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SMILES: Cc1nnc2CN=C(c3cc(CCc4ccc5OCCc5c4)sc3-n12)c1ccccc1Cl

InChI Key: InChIKey=YYFIKPSELURJMZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011864   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Homo sapiens (Human))		BDBM50011864
PNG
(4-(2-Chloro-phenyl)-2-[2-(2,3-dihydro-benzofuran-5...)
Show SMILES Cc1nnc2CN=C(c3cc(CCc4ccc5OCCc5c4)sc3-n12)c1ccccc1Cl |c:6|
Show InChI InChI=1S/C25H21ClN4OS/c1-15-28-29-23-14-27-24(19-4-2-3-5-21(19)26)20-13-18(32-25(20)30(15)23)8-6-16-7-9-22-17(12-16)10-11-31-22/h2-5,7,9,12-13H,6,8,10-11,14H2,1H3
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PubMed
n/an/a 20n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.

J Med Chem 34: 1440-6 (1991)


BindingDB Entry DOI: 10.7270/Q2BG2MZ9
More data for this
Ligand-Target Pair