BDBM50011868 4-(2-Chloro-phenyl)-2-[2-(4-cyclohexyl-phenyl)-ethyl]-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulene::CHEMBL432850

SMILES: Cc1nnc2CN=C(c3cc(CCc4ccc(cc4)C4CCCCC4)sc3-n12)c1ccccc1Cl

InChI Key: InChIKey=KVEJKTJWEFXFDT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50011868 (4-(2-Chloro-phenyl)-2-[2-(4-cyclohexyl-phenyl)-eth...) Show SMILES Cc1nnc2CN=C(c3cc(CCc4ccc(cc4)C4CCCCC4)sc3-n12)c1ccccc1Cl |c:6| Show InChI InChI=1S/C29H29ClN4S/c1-19-32-33-27-18-31-28(24-9-5-6-10-26(24)30)25-17-23(35-29(25)34(19)27)16-13-20-11-14-22(15-12-20)21-7-3-2-4-8-21/h5-6,9-12,14-15,17,21H,2-4,7-8,13,16,18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.				J Med Chem 34: 1440-6 (1991) BindingDB Entry DOI: 10.7270/Q2BG2MZ9
					More data for this Ligand-Target Pair