BDBM50011882 3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-2-yl]-3-hydrazono-1-morpholin-4-yl-propan-1-one::CHEMBL285199

SMILES: Cc1nnc2CN=C(c3cc(sc3-n12)C(CC(=O)N1CCOCC1)N=N)c1ccccc1Cl

InChI Key: InChIKey=RGTJSHALKBNINX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011882   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50011882 (3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...) Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C(CC(=O)N1CCOCC1)N=N)c1ccccc1Cl |c:6| Show InChI InChI=1S/C22H22ClN7O2S/c1-13-27-28-19-12-25-21(14-4-2-3-5-16(14)23)15-10-18(33-22(15)30(13)19)17(26-24)11-20(31)29-6-8-32-9-7-29/h2-5,10,17,24H,6-9,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.				J Med Chem 34: 1440-6 (1991) BindingDB Entry DOI: 10.7270/Q2BG2MZ9
					More data for this Ligand-Target Pair