BDBM50011954 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-methylsulfanyl-phenyl)-3H-quinazolin-4-one::CHEMBL285940

SMILES: CSc1ccc(cc1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O

InChI Key: InChIKey=RKANMAKGSIWYHT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (MOUSE)	BDBM50011954 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(4-methylsul...) Show SMILES CSc1ccc(cc1)-n1c(CCc2c[nH]c3ccc(Br)cc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H20BrN3OS/c1-31-19-10-8-18(9-11-19)29-24(28-23-5-3-2-4-20(23)25(29)30)13-6-16-15-27-22-12-7-17(26)14-21(16)22/h2-5,7-12,14-15,27H,6,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair