BDBM50012132 CHEMBL3263698

SMILES: CC(C)CN(Cc1ccc(s1)-c1cccc(NS(C)(=O)=O)c1)S(=O)(=O)Cc1ccccc1

InChI Key: InChIKey=VEQRHESMTIEDQE-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50012132 (CHEMBL3263698) Show SMILES CC(C)CN(Cc1ccc(s1)-c1cccc(NS(C)(=O)=O)c1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C23H28N2O4S3/c1-18(2)15-25(32(28,29)17-19-8-5-4-6-9-19)16-22-12-13-23(30-22)20-10-7-11-21(14-20)24-31(3,26)27/h4-14,18,24H,15-17H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Displacement of [3H2]25-hydroxycholesterol from human RORc-LBD after 3 hrs by scintillation counting				Bioorg Med Chem Lett 24: 2182-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.038 BindingDB Entry DOI: 10.7270/Q29K4CSN
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50012132 (CHEMBL3263698) Show SMILES CC(C)CN(Cc1ccc(s1)-c1cccc(NS(C)(=O)=O)c1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C23H28N2O4S3/c1-18(2)15-25(32(28,29)17-19-8-5-4-6-9-19)16-22-12-13-23(30-22)20-10-7-11-21(14-20)24-31(3,26)27/h4-14,18,24H,15-17H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inverse agonist activity at an N-terminal 6xHis-GST-tag human RORc-LBD assessed as inhibition of recruitment of the SRC1 co-activator peptide after 3...				Bioorg Med Chem Lett 24: 2182-7 (2014) Article DOI: 10.1016/j.bmcl.2014.03.038 BindingDB Entry DOI: 10.7270/Q29K4CSN
					More data for this Ligand-Target Pair